Published in Scientific Papers. Series D. Animal Science, Vol. LXVIII, Issue 1
Written by Nevyana STANCHEVA, Ivona DIMITROVA, Milena BOZHILOVA-SAKOVA
The ABCG2 gene is responsible for transporting many molecules across cell membranes and is expressed in various tissues, including the mammary gland. In this regard, the ABCG2 gene has been considered as a candidate gene related to the quantity, composition and quality of milk yield in sheep. The purpuse of present study was to establish the genetic diversity in this gene in connection with the study of possible dependencies of genotypes in ABCG2 with milk production in the ewes of the Awassi breed reared in Bulgaria. A highly polymorphic state of the ABCG2 gene was found, with the presence of two alleles - wild "+" and mutant "-" with frequencies of 0.49 and 0.51, respectively, and three genotypes - homozygous +/+ (0.31), heterozygous +/- (0.36 ) and homozygous -/- (0.33). Regarding milk productivity, no statistically significant differences were found between the different genotypes of the ABCG2 gene.
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